Unicorn Papers
Top ‱ cited papers from PUBMED
Unicorn Papers are based on an equal contribution (EC) citation model in which the total number of citations had been divided by the number of the authorsCurrently, the list contains 4058 papers with ECcit ≥ 968.5
‱ - permyriad,
, literally meaning "for (every) myriad (ten thousand)"
Volume 59, July 2025
| No. | Citations | ECcit | RCR | ECRCR | Title | Authors | Journal | Year | PMID | Article(?) |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 133791 | 66895.5 | 3288.6 | 1644.3 | Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. | K J Livak, T D Schmittgen | Methods | 2001 | 11846609 | Yes |
| 2 | 46366 | 46366.0 | 1379.9 | 1379.9 | A short history of SHELX. | George M Sheldrick | Acta Crystallogr A | 2008 | 18156677 | Yes |
| 3 | 38147 | 38147.0 | 1227.7 | 1227.7 | Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. | T Mosmann | J Immunol Methods | 1983 | 6606682 | Yes |
| 4 | 64669 | 32334.5 | 1933.1 | 966.5 | Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. | P Chomczynski, N Sacchi | Anal Biochem | 1987 | 2440339 | Yes |
| 5 | 28917 | 28917.0 | 673.4 | 673.4 | MUSCLE: multiple sequence alignment with high accuracy and high throughput. | Robert C Edgar | Nucleic Acids Res | 2004 | 15034147 | Yes |
| 6 | 28678 | 28678.0 | 622.8 | 622.8 | MicroRNAs: genomics, biogenesis, mechanism, and function. | David P Bartel | Cell | 2004 | 14744438 | False |
| 7 | 25896 | 25896.0 | 588.3 | 588.3 | A new mathematical model for relative quantification in real-time RT-PCR. | M W Pfaffl | Nucleic Acids Res | 2001 | 11328886 | Yes |
| 8 | 25253 | 25253.0 | 787.2 | 787.2 | Confidence Limits On Phylogenies: An Approach Using The Bootstrap. | Joseph Felsenstein | Evolution | 1985 | 28561359 | Yes |
| 9 | 46180 | 23090.0 | 1379.5 | 689.8 | Hallmarks of cancer: the next generation. | Douglas Hanahan, Robert A Weinberg | Cell | 2011 | 21376230 | False |
| 10 | 22139 | 22139.0 | 605.6 | 605.6 | Projector augmented-wave method. | P E Blöchl | Phys Rev B Condens Matter | 1994 | 9976227 | Yes |
| 11 | 21474 | 21474.0 | 729.4 | 729.4 | Density-functional exchange-energy approximation with correct asymptotic behavior. | A D Becke | Phys Rev A Gen Phys | 1988 | 9900728 | Yes |
| 12 | 41379 | 20689.5 | 1278.6 | 639.3 | The neighbor-joining method: a new method for reconstructing phylogenetic trees. | N Saitou, M Nei | Mol Biol Evol | 1987 | 3447015 | Yes |
| 13 | 56962 | 18987.3 | 2010.3 | 670.1 | Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. | Michael I Love, Wolfgang Huber, Simon Anders | Genome Biol | 2014 | 25516281 | Yes |
| 14 | 18954 | 18954.0 | 755.6 | 755.6 | RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies. | Alexandros Stamatakis | Bioinformatics | 2014 | 24451623 | Yes |
| 15 | 37648 | 18824.0 | 1760.1 | 880.0 | Statistical methods for assessing agreement between two methods of clinical measurement. | J M Bland, D G Altman | Lancet | 1986 | 2868172 | Yes |
| 16 | 18114 | 18114.0 | 668.0 | 668.0 | A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences. | M Kimura | J Mol Evol | 1980 | 7463489 | Yes |
| 17 | 54133 | 18044.3 | 1579.1 | 526.4 | Generalized Gradient Approximation Made Simple. | J P Perdew, K Burke, M Ernzerhof | Phys Rev Lett | 1996 | 10062328 | Yes |
| 18 | 35983 | 17991.5 | 1092.9 | 546.5 | Fast gapped-read alignment with Bowtie 2. | Ben Langmead, Steven L Salzberg | Nat Methods | 2012 | 22388286 | Yes |
| 19 | 17955 | 17955.0 | 734.8 | 734.8 | A power primer. | J Cohen | Psychol Bull | 1992 | 19565683 | Yes |
| 20 | 17228 | 17228.0 | 428.0 | 428.0 | Atherosclerosis--an inflammatory disease. | R Ross | N Engl J Med | 1999 | 9887164 | False |
| 21 | 33915 | 16957.5 | 833.3 | 416.6 | Fast and accurate short read alignment with Burrows-Wheeler transform. | Heng Li, Richard Durbin | Bioinformatics | 2009 | 19451168 | Yes |
| 22 | 32520 | 16260.0 | 1287.1 | 643.5 | The hospital anxiety and depression scale. | A S Zigmond, R P Snaith | Acta Psychiatr Scand | 1983 | 6880820 | Yes |
| 23 | 16149 | 16149.0 | 756.4 | 756.4 | Crystal structure refinement with SHELXL. | George M Sheldrick | Acta Crystallogr C Struct Chem | 2015 | 25567568 | Yes |
| 24 | 15946 | 15946.0 | 388.2 | 388.2 | MicroRNAs: target recognition and regulatory functions. | David P Bartel | Cell | 2009 | 19167326 | False |
| 25 | 31411 | 15705.5 | 1169.0 | 584.5 | Meta-analysis in clinical trials. | R DerSimonian, N Laird | Control Clin Trials | 1986 | 3802833 | Yes |
| 26 | 15554 | 15554.0 | 600.5 | 600.5 | Catalase in vitro. | H Aebi | Methods Enzymol | 1984 | 6727660 | Yes |
| 27 | 46065 | 15355.0 | 1309.6 | 436.5 | CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. | J D Thompson, D G Higgins, T J Gibson | Nucleic Acids Res | 1994 | 7984417 | Yes |
| 28 | 30096 | 15048.0 | 812.6 | 406.3 | Efficient iterative schemes for ab initio total-energy calculations using a plane-wave basis set. | G Kresse, J Furthmüller | Phys Rev B Condens Matter | 1996 | 9984901 | Yes |
| 29 | 13490 | 13490.0 | 331.9 | 331.9 | Xds. | Wolfgang Kabsch | Acta Crystallogr D Biol Crystallogr | 2010 | 20124692 | Yes |
| 30 | 13383 | 13383.0 | 510.9 | 510.9 | Investigation of the freely available easy-to-use software 'EZR' for medical statistics. | Y Kanda | Bone Marrow Transplant | 2013 | 23208313 | Yes |
| 31 | 26729 | 13364.5 | 541.2 | 270.6 | Coot: model-building tools for molecular graphics. | Paul Emsley, Kevin Cowtan | Acta Crystallogr D Biol Crystallogr | 2004 | 15572765 | Yes |
| 32 | 39996 | 13332.0 | 1471.4 | 490.5 | Trimmomatic: a flexible trimmer for Illumina sequence data. | Anthony M Bolger, Marc Lohse, Bjoern Usadel | Bioinformatics | 2014 | 24695404 | Yes |
| 33 | 66516 | 13303.2 | 1905.4 | 381.1 | Basic local alignment search tool. | S F Altschul, W Gish, W Miller, E W Myers, D J Lipman | J Mol Biol | 1990 | 2231712 | Yes |
| 34 | 26255 | 13127.5 | 700.5 | 350.2 | Quantifying heterogeneity in a meta-analysis. | Julian P T Higgins, Simon G Thompson | Stat Med | 2002 | 12111919 | Yes |
| 35 | 13114 | 13114.0 | 403.3 | 403.3 | Search and clustering orders of magnitude faster than BLAST. | Robert C Edgar | Bioinformatics | 2010 | 20709691 | Yes |
| 36 | 26038 | 13019.0 | 1054.4 | 527.2 | The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. | J E Ware, C D Sherbourne | Med Care | 1992 | 1593914 | Yes |
| 37 | 12946 | 12946.0 | 387.6 | 387.6 | The Psychophysics Toolbox. | D H Brainard | Spat Vis | 1997 | 9176952 | Yes |
| 38 | 12880 | 12880.0 | 432.4 | 432.4 | Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. | Andreas Stang | Eur J Epidemiol | 2010 | 20652370 | Yes |
| 39 | 38616 | 12872.0 | 1345.4 | 448.5 | Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density. | C Lee, W Yang, R G Parr | Phys Rev B Condens Matter | 1988 | 9944570 | Yes |
| 40 | 25186 | 12593.0 | 917.5 | 458.8 | MAFFT multiple sequence alignment software version 7: improvements in performance and usability. | Kazutaka Katoh, Daron M Standley | Mol Biol Evol | 2013 | 23329690 | Yes |
| 41 | 12308 | 12308.0 | 403.2 | 403.2 | Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). | J F Kurtzke | Neurology | 1983 | 6685237 | Yes |
| 42 | 36307 | 12102.3 | 939.8 | 313.3 | VMD: visual molecular dynamics. | W Humphrey, A Dalke, K Schulten | J Mol Graph | 1996 | 8744570 | Yes |
| 43 | 24068 | 12034.0 | 513.5 | 256.8 | KEGG: kyoto encyclopedia of genes and genomes. | M Kanehisa, S Goto | Nucleic Acids Res | 2000 | 10592173 | Yes |
| 44 | 24066 | 12033.0 | 519.2 | 259.6 | Processing of X-ray diffraction data collected in oscillation mode. | Z Otwinowski, W Minor | Methods Enzymol | 1997 | 27754618 | Yes |
| 45 | 35532 | 11844.0 | 1145.9 | 382.0 | NIH Image to ImageJ: 25 years of image analysis. | Caroline A Schneider, Wayne S Rasband, Kevin W Eliceiri | Nat Methods | 2012 | 22930834 | False |
| 46 | 11779 | 11779.0 | 444.5 | 444.5 | A new method for measuring daytime sleepiness: the Epworth sleepiness scale. | M W Johns | Sleep | 1991 | 1798888 | Yes |
| 47 | 11711 | 11711.0 | 497.7 | 497.7 | Prokka: rapid prokaryotic genome annotation. | Torsten Seemann | Bioinformatics | 2014 | 24642063 | Yes |
| 48 | 45214 | 11303.5 | 1272.4 | 318.1 | Measuring inconsistency in meta-analyses. | Julian P T Higgins, Simon G Thompson, Jonathan J Deeks, Douglas G Altman | BMJ | 2003 | 12958120 | False |
| 49 | 21925 | 10962.5 | 921.3 | 460.6 | The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. | R M Baron, D A Kenny | J Pers Soc Psychol | 1986 | 3806354 | Yes |
| 50 | 21557 | 10778.5 | 555.9 | 277.9 | A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. | A P Feinberg, B Vogelstein | Anal Biochem | 1983 | 6312838 | Yes |
| 51 | 10776 | 10776.0 | 356.6 | 356.6 | Structure validation in chemical crystallography. | Anthony L Spek | Acta Crystallogr D Biol Crystallogr | 2009 | 19171970 | Yes |
| 52 | 10713 | 10713.0 | 491.7 | 491.7 | SHELXT - integrated space-group and crystal-structure determination. | George M Sheldrick | Acta Crystallogr A Found Adv | 2015 | 25537383 | Yes |
| 53 | 10711 | 10711.0 | 274.2 | 274.2 | Semiempirical GGA-type density functional constructed with a long-range dispersion correction. | Stefan Grimme | J Comput Chem | 2006 | 16955487 | Yes |
| 54 | 10278 | 10278.0 | 435.3 | 435.3 | Psychophysical bases of perceived exertion. | G A Borg | Med Sci Sports Exerc | 1982 | 7154893 | Yes |
| 55 | 10115 | 10115.0 | 281.0 | 281.0 | The blockade of immune checkpoints in cancer immunotherapy. | Drew M Pardoll | Nat Rev Cancer | 2012 | 22437870 | False |
| 56 | 10083 | 10083.0 | 285.3 | 285.3 | Evolutionary trees from DNA sequences: a maximum likelihood approach. | J Felsenstein | J Mol Evol | 1981 | 7288891 | Yes |
| 57 | 39766 | 9941.5 | 1446.8 | 361.7 | A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. | M E Charlson, P Pompei, K L Ales, C R MacKenzie | J Chronic Dis | 1987 | 3558716 | Yes |
| 58 | 9935 | 9935.0 | 202.6 | 202.6 | Mfold web server for nucleic acid folding and hybridization prediction. | Michael Zuker | Nucleic Acids Res | 2003 | 12824337 | Yes |
| 59 | 39002 | 9750.5 | 1250.3 | 312.6 | Bias in meta-analysis detected by a simple, graphical test. | M Egger, G Davey Smith, M Schneider, C Minder | BMJ | 1997 | 9310563 | Yes |
| 60 | 9705 | 9705.0 | 272.5 | 272.5 | Vitamin D deficiency. | Michael F Holick | N Engl J Med | 2007 | 17634462 | False |
| 61 | 19305 | 9652.5 | 495.5 | 247.8 | A simple method for displaying the hydropathic character of a protein. | J Kyte, R F Doolittle | J Mol Biol | 1982 | 7108955 | Yes |
| 62 | 9575 | 9575.0 | 316.9 | 316.9 | Banting lecture 1988. Role of insulin resistance in human disease. | G M Reaven | Diabetes | 1988 | 3056758 | False |
| 63 | 19130 | 9565.0 | 491.2 | 245.6 | Analyzing real-time PCR data by the comparative C(T) method. | Thomas D Schmittgen, Kenneth J Livak | Nat Protoc | 2008 | 18546601 | Yes |
| 64 | 9546 | 9546.0 | 225.7 | 225.7 | PAML 4: phylogenetic analysis by maximum likelihood. | Ziheng Yang | Mol Biol Evol | 2007 | 17483113 | Yes |
| 65 | 9523 | 9523.0 | 241.7 | 241.7 | RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models. | Alexandros Stamatakis | Bioinformatics | 2006 | 16928733 | Yes |
| 66 | 28449 | 9483.0 | 731.4 | 243.8 | edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. | Mark D Robinson, Davis J McCarthy, Gordon K Smyth | Bioinformatics | 2010 | 19910308 | Yes |
| 67 | 28444 | 9481.3 | 822.6 | 274.2 | The PHQ-9: validity of a brief depression severity measure. | K Kroenke, R L Spitzer, J B Williams | J Gen Intern Med | 2001 | 11556941 | Yes |
| 68 | 9473 | 9473.0 | 250.2 | 250.2 | Studies on transformation of Escherichia coli with plasmids. | D Hanahan | J Mol Biol | 1983 | 6345791 | Yes |
| 69 | 18867 | 9433.5 | 389.2 | 194.6 | The hallmarks of cancer. | D Hanahan, R A Weinberg | Cell | 2000 | 10647931 | False |
| 70 | 9413 | 9413.0 | 243.6 | 243.6 | Canonical dynamics: Equilibrium phase-space distributions. | WG Hoover | Phys Rev A Gen Phys | 1985 | 9895674 | Yes |
| 71 | 9372 | 9372.0 | 375.2 | 375.2 | UPARSE: highly accurate OTU sequences from microbial amplicon reads. | Robert C Edgar | Nat Methods | 2013 | 23955772 | Yes |
| 72 | 27934 | 9311.3 | 692.8 | 230.9 | Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. | Da Wei Huang, Brad T Sherman, Richard A Lempicki | Nat Protoc | 2009 | 19131956 | Yes |
| 73 | 9253 | 9253.0 | 262.6 | 262.6 | Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose. | P S Thomas | Proc Natl Acad Sci U S A | 1980 | 6159641 | Yes |
| 74 | 9195 | 9195.0 | 258.0 | 258.0 | The pathogenesis of atherosclerosis: a perspective for the 1990s. | R Ross | Nature | 1993 | 8479518 | False |
| 75 | 18302 | 9151.0 | 543.1 | 271.6 | AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading. | Oleg Trott, Arthur J Olson | J Comput Chem | 2010 | 19499576 | Yes |
| 76 | 9084 | 9084.0 | 233.8 | 233.8 | Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. | M C Hochberg | Arthritis Rheum | 1997 | 9324032 | Yes |
| 77 | 18145 | 9072.5 | 389.4 | 194.7 | Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. | Kazutoshi Takahashi, Shinya Yamanaka | Cell | 2006 | 16904174 | Yes |
| 78 | 9070 | 9070.0 | 232.2 | 232.2 | Integrins: versatility, modulation, and signaling in cell adhesion. | R O Hynes | Cell | 1992 | 1555235 | False |
| 79 | 9039 | 9039.0 | 231.5 | 231.5 | Apoptosis: a review of programmed cell death. | Susan Elmore | Toxicol Pathol | 2007 | 17562483 | False |
| 80 | 8899 | 8899.0 | 176.4 | 176.4 | Linear models and empirical bayes methods for assessing differential expression in microarray experiments. | Gordon K Smyth | Stat Appl Genet Mol Biol | 2004 | 16646809 | Yes |
| 81 | 26676 | 8892.0 | 1353.3 | 451.1 | MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for Bigger Datasets. | Sudhir Kumar, Glen Stecher, Koichiro Tamura | Mol Biol Evol | 2016 | 27004904 | Yes |
| 82 | 17609 | 8804.5 | 406.4 | 203.2 | BEDTools: a flexible suite of utilities for comparing genomic features. | Aaron R Quinlan, Ira M Hall | Bioinformatics | 2010 | 20110278 | Yes |
| 83 | 8788 | 8788.0 | 183.5 | 183.5 | The functions of animal microRNAs. | Victor Ambros | Nature | 2004 | 15372042 | False |
| 84 | 8701 | 8701.0 | 254.8 | 254.8 | AFNI: software for analysis and visualization of functional magnetic resonance neuroimages. | R W Cox | Comput Biomed Res | 1996 | 8812068 | Yes |
| 85 | 17090 | 8545.0 | 562.8 | 281.4 | Three approaches to qualitative content analysis. | Hsiu-Fang Hsieh, Sarah E Shannon | Qual Health Res | 2005 | 16204405 | Yes |
| 86 | 33626 | 8406.5 | 1084.8 | 271.2 | G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. | Franz Faul, Edgar Erdfelder, Albert-Georg Lang, Axel Buchner | Behav Res Methods | 2007 | 17695343 | Yes |
| 87 | 8392 | 8392.0 | 384.5 | 384.5 | Comparative fit indexes in structural models. | P M Bentler | Psychol Bull | 1990 | 2320703 | Yes |
| 88 | 16516 | 8258.0 | 369.3 | 184.7 | Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana. | S J Clough, A F Bent | Plant J | 1998 | 10069079 | Yes |
| 89 | 24741 | 8247.0 | 736.6 | 245.5 | Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. | Daniel Dindo, Nicolas Demartines, Pierre-Alain Clavien | Ann Surg | 2004 | 15273542 | Yes |
| 90 | 8134 | 8134.0 | 219.6 | 219.6 | Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. | F Tajima | Genetics | 1989 | 2513255 | Yes |
| 91 | 16260 | 8130.0 | 376.6 | 188.3 | WGCNA: an R package for weighted correlation network analysis. | Peter Langfelder, Steve Horvath | BMC Bioinformatics | 2008 | 19114008 | Yes |
| 92 | 16057 | 8028.5 | 387.1 | 193.6 | MrBayes 3: Bayesian phylogenetic inference under mixed models. | Fredrik Ronquist, John P Huelsenbeck | Bioinformatics | 2003 | 12912839 | Yes |
| 93 | 7959 | 7959.0 | 193.8 | 193.8 | Fast robust automated brain extraction. | Stephen M Smith | Hum Brain Mapp | 2002 | 12391568 | False |
| 94 | 7906 | 7906.0 | 217.9 | 217.9 | "Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate--polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. | W N Burnette | Anal Biochem | 1981 | 6266278 | Yes |
| 95 | 7835 | 7835.0 | 163.5 | 163.5 | Chromatin modifications and their function. | Tony Kouzarides | Cell | 2007 | 17320507 | False |
| 96 | 15609 | 7804.5 | 965.9 | 482.9 | A Guideline of Selecting and Reporting Intraclass Correlation Coefficients for Reliability Research. | Terry K Koo, Mae Y Li | J Chiropr Med | 2016 | 27330520 | Yes |
| 97 | 7796 | 7796.0 | 215.6 | 215.6 | The role of protein kinase C in cell surface signal transduction and tumour promotion. | Y Nishizuka | Nature | 1984 | 6232463 | False |
| 98 | 7752 | 7752.0 | 243.0 | 243.0 | The Clinical Dementia Rating (CDR): current version and scoring rules. | J C Morris | Neurology | 1993 | 8232972 | Yes |
| 99 | 7747 | 7747.0 | 253.0 | 253.0 | Density-functional approximation for the correlation energy of the inhomogeneous electron gas. | J P Perdew | Phys Rev B Condens Matter | 1986 | 9938299 | Yes |
| 100 | 7633 | 7633.0 | 227.9 | 227.9 | The VideoToolbox software for visual psychophysics: transforming numbers into movies. | D G Pelli | Spat Vis | 1997 | 9176953 | Yes |
| 101 | 7626 | 7626.0 | 264.5 | 264.5 | The Strengths and Difficulties Questionnaire: a research note. | R Goodman | J Child Psychol Psychiatry | 1997 | 9255702 | Yes |
| 102 | 7624 | 7624.0 | 324.8 | 324.8 | Interrater reliability: the kappa statistic. | Mary L McHugh | Biochem Med (Zagreb) | 2012 | 23092060 | Yes |
| 103 | 22755 | 7585.0 | 783.1 | 261.0 | Consolidated criteria for reporting qualitative research (COREQ): a 32-item checklist for interviews and focus groups. | Allison Tong, Peter Sainsbury, Jonathan Craig | Int J Qual Health Care | 2007 | 17872937 | Yes |
| 104 | 7569 | 7569.0 | 323.7 | 323.7 | Minimap2: pairwise alignment for nucleotide sequences. | Heng Li | Bioinformatics | 2018 | 29750242 | Yes |
| 105 | 52691 | 7527.3 | 1346.3 | 192.3 | Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. | S F Altschul, T L Madden, A A Schäffer, J Zhang, Z Zhang, W Miller, D J Lipman | Nucleic Acids Res | 1997 | 9254694 | False |
| 106 | 14794 | 7397.0 | 406.1 | 203.1 | EEGLAB: an open source toolbox for analysis of single-trial EEG dynamics including independent component analysis. | Arnaud Delorme, Scott Makeig | J Neurosci Methods | 2004 | 15102499 | Yes |
| 107 | 7313 | 7313.0 | 188.5 | 188.5 | A modified poisson regression approach to prospective studies with binary data. | Guangyong Zou | Am J Epidemiol | 2004 | 15033648 | Yes |
| 108 | 7200 | 7200.0 | 237.4 | 237.4 | An Introduction to Propensity Score Methods for Reducing the Effects of Confounding in Observational Studies. | Peter C Austin | Multivariate Behav Res | 2011 | 21818162 | Yes |
| 109 | 14354 | 7177.0 | 385.5 | 192.8 | RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome. | Bo Li, Colin N Dewey | BMC Bioinformatics | 2011 | 21816040 | Yes |
| 110 | 7081 | 7081.0 | 191.8 | 191.8 | TreeView: an application to display phylogenetic trees on personal computers. | R D Page | Comput Appl Biosci | 1996 | 8902363 | Yes |
| 111 | 14034 | 7017.0 | 362.1 | 181.1 | Balanced basis sets of split valence, triple zeta valence and quadruple zeta valence quality for H to Rn: Design and assessment of accuracy. | Florian Weigend, Reinhart Ahlrichs | Phys Chem Chem Phys | 2005 | 16240044 | Yes |
| 112 | 6850 | 6850.0 | 182.9 | 182.9 | The steroid and thyroid hormone receptor superfamily. | R M Evans | Science | 1988 | 3283939 | False |
| 113 | 6710 | 6710.0 | 131.2 | 131.2 | Integrins: bidirectional, allosteric signaling machines. | Richard O Hynes | Cell | 2002 | 12297042 | False |
| 114 | 6678 | 6678.0 | 216.2 | 216.2 | Ethical guidelines for investigations of experimental pain in conscious animals. | Manfred Zimmermann | Pain | 1983 | 6877845 | False |
| 115 | 6612 | 6612.0 | 152.6 | 152.6 | Inflammation, atherosclerosis, and coronary artery disease. | Göran K Hansson | N Engl J Med | 2005 | 15843671 | False |
| 116 | 19788 | 6596.0 | 552.4 | 184.1 | A new generation of Ca2+ indicators with greatly improved fluorescence properties. | G Grynkiewicz, M Poenie, R Y Tsien | J Biol Chem | 1985 | 3838314 | Yes |
| 117 | 6591 | 6591.0 | 169.3 | 169.3 | Angiogenesis in cancer, vascular, rheumatoid and other disease. | J Folkman | Nat Med | 1995 | 7584949 | False |
| 118 | 6591 | 6591.0 | 150.4 | 150.4 | Selection of conserved blocks from multiple alignments for their use in phylogenetic analysis. | J Castresana | Mol Biol Evol | 2000 | 10742046 | Yes |
| 119 | 6566 | 6566.0 | 170.7 | 170.7 | Adhesion receptors of the immune system. | T A Springer | Nature | 1990 | 1974032 | False |
| 120 | 13054 | 6527.0 | 442.1 | 221.1 | The meaning and use of the area under a receiver operating characteristic (ROC) curve. | J A Hanley, B J McNeil | Radiology | 1982 | 7063747 | Yes |
| 121 | 6414 | 6414.0 | 135.3 | 135.3 | p53, the cellular gatekeeper for growth and division. | A J Levine | Cell | 1997 | 9039259 | False |
| 122 | 6411 | 6411.0 | 128.8 | 128.8 | Rapid and efficient site-specific mutagenesis without phenotypic selection. | T A Kunkel | Proc Natl Acad Sci U S A | 1985 | 3881765 | Yes |
| 123 | 6393 | 6393.0 | 148.3 | 148.3 | Biochemistry and molecular cell biology of diabetic complications. | M Brownlee | Nature | 2001 | 11742414 | Yes |
| 124 | 6385 | 6385.0 | 150.6 | 150.6 | Inflammation and metabolic disorders. | Gökhan S Hotamisligil | Nature | 2006 | 17167474 | False |
| 125 | 6362 | 6362.0 | 136.7 | 136.7 | Inflammation in atherosclerosis. | Peter Libby | Nature | 2002 | 12490960 | False |
| 126 | 6360 | 6360.0 | 146.7 | 146.7 | Free radicals in the physiological control of cell function. | Wulf Dröge | Physiol Rev | 2002 | 11773609 | False |
| 127 | 6354 | 6354.0 | 190.4 | 190.4 | Prejudice, social stress, and mental health in lesbian, gay, and bisexual populations: conceptual issues and research evidence. | Ilan H Meyer | Psychol Bull | 2003 | 12956539 | False |
| 128 | 12654 | 6327.0 | 438.4 | 219.2 | Multiwfn: a multifunctional wavefunction analyzer. | Tian Lu, Feiwu Chen | J Comput Chem | 2012 | 22162017 | Yes |
| 129 | 6295 | 6295.0 | 116.1 | 116.1 | BLAT--the BLAST-like alignment tool. | W James Kent | Genome Res | 2002 | 11932250 | Yes |
| 130 | 6133 | 6133.0 | 139.2 | 139.2 | Antimicrobial peptides of multicellular organisms. | Michael Zasloff | Nature | 2002 | 11807545 | Yes |
| 131 | 12240 | 6120.0 | 331.2 | 165.6 | Neuropathological stageing of Alzheimer-related changes. | H Braak, E Braak | Acta Neuropathol | 1991 | 1759558 | False |
| 132 | 12219 | 6109.5 | 294.6 | 147.3 | MRBAYES: Bayesian inference of phylogenetic trees. | J P Huelsenbeck, F Ronquist | Bioinformatics | 2001 | 11524383 | Yes |
| 133 | 6106 | 6106.0 | 167.1 | 167.1 | A fast diffeomorphic image registration algorithm. | John Ashburner | Neuroimage | 2007 | 17761438 | Yes |
| 134 | 12153 | 6076.5 | 277.9 | 138.9 | Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features. | W Kabsch, C Sander | Biopolymers | 1983 | 6667333 | Yes |
| 135 | 6074 | 6074.0 | 147.3 | 147.3 | Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. | T A Springer | Cell | 1994 | 7507411 | False |
| 136 | 12141 | 6070.5 | 260.7 | 130.3 | One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. | K A Datsenko, B L Wanner | Proc Natl Acad Sci U S A | 2000 | 10829079 | Yes |
| 137 | 6068 | 6068.0 | 152.5 | 152.5 | G proteins: transducers of receptor-generated signals. | A G Gilman | Annu Rev Biochem | 1987 | 3113327 | False |
| 138 | 36213 | 6035.5 | 1230.7 | 205.1 | Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support. | Paul A Harris, Robert Taylor, Robert Thielke, Jonathon Payne, Nathaniel Gonzalez, Jose G Conde | J Biomed Inform | 2009 | 18929686 | Yes |
| 139 | 6033 | 6033.0 | 151.2 | 151.2 | Inositol trisphosphate and calcium signalling. | M J Berridge | Nature | 1993 | 8381210 | False |
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| 1845 | 2918 | 1459.0 | 91.4 | 45.7 | The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease. | W R Gibb, A J Lees | J Neurol Neurosurg Psychiatry | 1988 | 2841426 | False |
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| 1850 | 2909 | 1454.5 | 86.0 | 43.0 | The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. | J D Hayes, D J Pulford | Crit Rev Biochem Mol Biol | 1995 | 8770536 | False |
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| 1860 | 2903 | 1451.5 | 79.5 | 39.8 | A rapid boiling method for the preparation of bacterial plasmids. | D S Holmes, M Quigley | Anal Biochem | 1981 | 6269464 | Yes |
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| 1870 | 2898 | 1449.0 | 85.8 | 42.9 | Unidentified curved bacilli on gastric epithelium in active chronic gastritis. | J R Warren, B Marshall | Lancet | 1983 | 6134060 | Yes |
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| 1882 | 2885 | 1442.5 | 62.6 | 31.3 | The pathophysiology and treatment of sepsis. | Richard S Hotchkiss, Irene E Karl | N Engl J Med | 2003 | 12519925 | False |
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| 1885 | 2882 | 1441.0 | 79.7 | 39.9 | Defining the clinical course of multiple sclerosis: results of an international survey. National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis. | F D Lublin, S C Reingold | Neurology | 1996 | 8780061 | Yes |
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| 1992 | 1400 | 1400.0 | 43.1 | 43.1 | Glutathione metabolism and its selective modification. | A Meister | J Biol Chem | 1988 | 3053703 | False |
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| 1998 | 1398 | 1398.0 | 34.5 | 34.5 | Comparative physiology of salt and water stress. | R. Munns | Plant Cell Environ | 2002 | 11841667 | Yes |
| 1999 | 5589 | 1397.2 | 132.1 | 33.0 | CHARMM-GUI: a web-based graphical user interface for CHARMM. | Sunhwan Jo, Taehoon Kim, Vidyashankara G Iyer, Wonpil Im | J Comput Chem | 2008 | 18351591 | False |
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| 2006 | 1393 | 1393.0 | 56.4 | 56.4 | Environmentally induced oxidative stress in aquatic animals. | Volodymyr I Lushchak | Aquat Toxicol | 2011 | 21074869 | False |
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| 2008 | 2784 | 1392.0 | 178.7 | 89.3 | Reactive oxygen species (ROS) as pleiotropic physiological signalling agents. | Helmut Sies, Dean P Jones | Nat Rev Mol Cell Biol | 2020 | 32231263 | False |
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| 2791 | 1181 | 1181.0 | 43.7 | 43.7 | Second generation logarithmic estimates of single-pool variable volume Kt/V: an analysis of error. | J T Daugirdas | J Am Soc Nephrol | 1993 | 8305648 | Yes |
| 2792 | 1181 | 1181.0 | 39.4 | 39.4 | beta-Lactamases in laboratory and clinical resistance. | D M Livermore | Clin Microbiol Rev | 1995 | 8665470 | False |
| 2793 | 11808 | 1180.8 | 382.1 | 38.2 | The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. | N K Aaronson, S Ahmedzai, B Bergman, M Bullinger, A Cull, N J Duez, A Filiberti, H Flechtner, S B Fleishman, J C de Haes | J Natl Cancer Inst | 1993 | 8433390 | Yes |
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| 2795 | 8261 | 1180.1 | 239.4 | 34.2 | pROC: an open-source package for R and S+ to analyze and compare ROC curves. | Xavier Robin, Natacha Turck, Alexandre Hainard, Natalia Tiberti, Frédérique Lisacek, Jean-Charles Sanchez, Markus Müller | BMC Bioinformatics | 2011 | 21414208 | Yes |
| 2796 | 1180 | 1180.0 | 37.2 | 37.2 | Relations between the statistics of natural images and the response properties of cortical cells. | D J Field | J Opt Soc Am A | 1987 | 3430225 | Yes |
| 2797 | 1180 | 1180.0 | 26.7 | 26.7 | Hybridization of denatured RNA transferred or dotted nitrocellulose paper. | P S Thomas | Methods Enzymol | 1983 | 6194404 | Yes |
| 2798 | 1179 | 1179.0 | 51.5 | 51.5 | Presynaptic regulation of the release of catecholamines. | S Z Langer | Pharmacol Rev | 1980 | 6267618 | Yes |
| 2799 | 1179 | 1179.0 | 36.2 | 36.2 | Strategies of antioxidant defense. | H Sies | Eur J Biochem | 1993 | 7688300 | False |
| 2800 | 2358 | 1179.0 | 49.5 | 24.8 | Functions of lipid rafts in biological membranes. | D A Brown, E London | Annu Rev Cell Dev Biol | 1998 | 9891780 | False |
| 2801 | 1179 | 1179.0 | 41.6 | 41.6 | Relativistic electronic-structure calculations employing a two-component no-pair formalism with external-field projection operators. | B A Hess | Phys Rev A Gen Phys | 1986 | 9897114 | Yes |
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| 2809 | 1178 | 1178.0 | 32.7 | 32.7 | Phosphoinositides: tiny lipids with giant impact on cell regulation. | Tamas Balla | Physiol Rev | 2013 | 23899561 | False |
| 2810 | 1177 | 1177.0 | 34.7 | 34.7 | Low-molecular-weight heparins. | J I Weitz | N Engl J Med | 1997 | 9278467 | False |
| 2811 | 1177 | 1177.0 | 20.8 | 20.8 | Micro RNAs are complementary to 3' UTR sequence motifs that mediate negative post-transcriptional regulation. | Eric C Lai | Nat Genet | 2002 | 11896390 | Yes |
| 2812 | 11767 | 1176.7 | 261.5 | 26.1 | Scalable molecular dynamics with NAMD. | James C Phillips, Rosemary Braun, Wei Wang, James Gumbart, Emad Tajkhorshid, Elizabeth Villa, Christophe Chipot, Robert D Skeel, Laxmikant Kalé, Klaus Schulten | J Comput Chem | 2005 | 16222654 | Yes |
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| 2815 | 1175 | 1175.0 | 79.5 | 79.5 | Root canal anatomy of the human permanent teeth. | F J Vertucci | Oral Surg Oral Med Oral Pathol | 1984 | 6595621 | Yes |
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| 2818 | 7045 | 1174.2 | 158.7 | 26.4 | Enzymatic assembly of DNA molecules up to several hundred kilobases. | Daniel G Gibson, Lei Young, Ray-Yuan Chuang, J Craig Venter, Clyde A Hutchison, Hamilton O Smith | Nat Methods | 2009 | 19363495 | Yes |
| 2819 | 1174 | 1174.0 | 26.2 | 26.2 | The columnar organization of the neocortex. | V B Mountcastle | Brain | 1997 | 9153131 | False |
| 2820 | 1174 | 1174.0 | 31.8 | 31.8 | Pharmacology of cannabinoid CB1 and CB2 receptors. | R G Pertwee | Pharmacol Ther | 1997 | 9336020 | False |
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| 2824 | 1173 | 1173.0 | 36.6 | 36.6 | Molecular biology of steroid hormone synthesis. | W L Miller | Endocr Rev | 1988 | 3061784 | False |
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| 2826 | 1173 | 1173.0 | 22.7 | 22.7 | Models, mechanisms and clinical evidence for cancer dormancy. | Julio A Aguirre-Ghiso | Nat Rev Cancer | 2007 | 17957189 | False |
| 2827 | 1172 | 1172.0 | 23.9 | 23.9 | Version 1.2 of the Crystallography and NMR system. | Axel T Brunger | Nat Protoc | 2007 | 18007608 | Yes |
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| 2834 | 1171 | 1171.0 | 57.5 | 57.5 | Osseointegration and its experimental background. | P I Brånemark | J Prosthet Dent | 1983 | 6352924 | False |
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| 2848 | 2334 | 1167.0 | 67.0 | 33.5 | Excitatory amino acids as a final common pathway for neurologic disorders. | S A Lipton, P A Rosenberg | N Engl J Med | 1994 | 7905600 | False |
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| 2851 | 2334 | 1167.0 | 56.4 | 28.2 | The regulation of IL-10 production by immune cells. | Margarida Saraiva, Anne O'Garra | Nat Rev Immunol | 2010 | 20154735 | False |
| 2852 | 1167 | 1167.0 | 31.9 | 31.9 | Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy. | Gregg L Semenza | Trends Pharmacol Sci | 2012 | 22398146 | False |
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| 2855 | 1166 | 1166.0 | 42.3 | 42.3 | Type 2 inflammation in asthma--present in most, absent in many. | John V Fahy | Nat Rev Immunol | 2015 | 25534623 | False |
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| 2861 | 2330 | 1165.0 | 43.5 | 21.8 | NF-kappaB at the crossroads of life and death. | Michael Karin, Anning Lin | Nat Immunol | 2002 | 11875461 | False |
| 2862 | 1165 | 1165.0 | 34.1 | 34.1 | Lanthanide luminescence for biomedical analyses and imaging. | Jean-Claude G Bünzli | Chem Rev | 2010 | 20151630 | False |
| 2863 | 1165 | 1165.0 | 33.5 | 33.5 | Periodontitis: a polymicrobial disruption of host homeostasis. | Richard P Darveau | Nat Rev Microbiol | 2010 | 20514045 | False |
| 2864 | 2329 | 1164.5 | 76.7 | 38.4 | Pharmaceuticals and personal care products in the environment: agents of subtle change? | C G Daughton, T A Ternes | Environ Health Perspect | 1999 | 10592150 | False |
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| 2866 | 1164 | 1164.0 | 55.6 | 55.6 | The sociological study of stress. | L I Pearlin | J Health Soc Behav | 1989 | 2674272 | False |
| 2867 | 1164 | 1164.0 | 33.5 | 33.5 | pegas: an R package for population genetics with an integrated-modular approach. | Emmanuel Paradis | Bioinformatics | 2010 | 20080509 | Yes |
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| 2872 | 1163 | 1163.0 | 31.3 | 31.3 | Venous thrombosis: a multicausal disease. | F R Rosendaal | Lancet | 1999 | 10209995 | False |
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| 2881 | 1161 | 1161.0 | 28.2 | 28.2 | Model for a quantum Hall effect without Landau levels: Condensed-matter realization of the "parity anomaly" | F D Haldane | Phys Rev Lett | 1988 | 10038961 | Yes |
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| 2883 | 1160 | 1160.0 | 42.5 | 42.5 | Omega-3 fatty acids in health and disease and in growth and development. | A P Simopoulos | Am J Clin Nutr | 1991 | 1908631 | False |
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| 2899 | 1157 | 1157.0 | 28.8 | 28.8 | Epidemiology of urinary tract infections: incidence, morbidity, and economic costs. | Betsy Foxman | Am J Med | 2002 | 12113866 | False |
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| 3068 | 1123 | 1123.0 | 31.7 | 31.7 | Vascular Endothelial Growth Factor (VEGF) and Its Receptor (VEGFR) Signaling in Angiogenesis: A Crucial Target for Anti- and Pro-Angiogenic Therapies. | Masabumi Shibuya | Genes Cancer | 2011 | 22866201 | Yes |
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| 3748 | 1013 | 1013.0 | 51.1 | 51.1 | The importance of antioxidants which play the role in cellular response against oxidative/nitrosative stress: current state. | Ergul Belge Kurutas | Nutr J | 2016 | 27456681 | False |
| 3749 | 2025 | 1012.5 | 45.4 | 22.7 | Signal integration by JNK and p38 MAPK pathways in cancer development. | Erwin F Wagner, Angel R Nebreda | Nat Rev Cancer | 2009 | 19629069 | False |
| 3750 | 1012 | 1012.0 | 21.7 | 21.7 | Potential metal-binding domains in nucleic acid binding proteins. | J M Berg | Science | 1986 | 2421409 | Yes |
| 3751 | 1012 | 1012.0 | 22.8 | 22.8 | Diffraction methods for biological macromolecules. Interactive computer graphics: FRODO. | T A Jones | Methods Enzymol | 1985 | 3841179 | Yes |
| 3752 | 2024 | 1012.0 | 68.8 | 34.4 | Structure of serum albumin. | D C Carter, J X Ho | Adv Protein Chem | 1994 | 8154369 | False |
| 3753 | 1012 | 1012.0 | 31.5 | 31.5 | Comparison of the gastrointestinal anatomy, physiology, and biochemistry of humans and commonly used laboratory animals. | T T Kararli | Biopharm Drug Dispos | 1995 | 8527686 | False |
| 3754 | 1012 | 1012.0 | 30.3 | 30.3 | Properties of osteoconductive biomaterials: calcium phosphates. | Racquel Zapanta LeGeros | Clin Orthop Relat Res | 2002 | 11937868 | False |
| 3755 | 1012 | 1012.0 | 17.6 | 17.6 | Protein kinase CK2: structure, regulation and role in cellular decisions of life and death. | David W Litchfield | Biochem J | 2003 | 12396231 | False |
| 3756 | 1012 | 1012.0 | 26.7 | 26.7 | Controlled microwave heating in modern organic synthesis. | C Oliver Kappe | Angew Chem Int Ed Engl | 2004 | 15558676 | False |
| 3757 | 2023 | 1011.5 | 34.7 | 17.4 | Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. | J P Morgenstern, H Land | Nucleic Acids Res | 1990 | 2194165 | Yes |
| 3758 | 14159 | 1011.4 | 999.2 | 71.4 | Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. | Dawei Wang, Bo Hu, Chang Hu, Fangfang Zhu, Xing Liu, Jing Zhang, Binbin Wang, Hui Xiang, Zhenshun Cheng, Yong Xiong, Yan Zhao, Yirong Li, Xinghuan Wang, Zhiyong Peng | JAMA | 2020 | 32031570 | Yes |
| 3759 | 1011 | 1011.0 | 29.6 | 29.6 | Classes of calcium channels in vertebrate cells. | B P Bean | Annu Rev Physiol | 1989 | 2540697 | False |
| 3760 | 1011 | 1011.0 | 35.5 | 35.5 | Hand and sex differences in the isthmus and genu of the human corpus callosum. A postmortem morphological study. | S F Witelson | Brain | 1989 | 2731030 | Yes |
| 3761 | 1011 | 1011.0 | 29.3 | 29.3 | Nitric oxide synthase structure and mechanism. | M A Marletta | J Biol Chem | 1993 | 7685338 | False |
| 3762 | 1011 | 1011.0 | 34.2 | 34.2 | The emotion probe. Studies of motivation and attention. | P J Lang | Am Psychol | 1995 | 7762889 | Yes |
| 3763 | 2022 | 1011.0 | 63.1 | 31.6 | Long-term impact of initial surgical and medical therapy on papillary and follicular thyroid cancer. | E L Mazzaferri, S M Jhiang | Am J Med | 1994 | 7977430 | Yes |
| 3764 | 2022 | 1011.0 | 51.9 | 25.9 | Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. | M Tsujii, R N DuBois | Cell | 1995 | 8521479 | Yes |
| 3765 | 2022 | 1011.0 | 44.0 | 22.0 | Caspases: killer proteases. | D W Nicholson, N A Thornberry | Trends Biochem Sci | 1997 | 9270303 | False |
| 3766 | 2022 | 1011.0 | 53.4 | 26.7 | The use of the elevated plus maze as an assay of anxiety-related behavior in rodents. | Alicia A Walf, Cheryl A Frye | Nat Protoc | 2007 | 17406592 | Yes |
| 3767 | 2021 | 1010.5 | 44.3 | 22.1 | Reactive oxygen species in cell signaling. | V J Thannickal, B L Fanburg | Am J Physiol Lung Cell Mol Physiol | 2000 | 11076791 | False |
| 3768 | 2021 | 1010.5 | 47.3 | 23.6 | ARAGORN, a program to detect tRNA genes and tmRNA genes in nucleotide sequences. | Dean Laslett, Bjorn Canback | Nucleic Acids Res | 2004 | 14704338 | Yes |
| 3769 | 1010 | 1010.0 | 32.8 | 32.8 | Substrate recognition sites in cytochrome P450 family 2 (CYP2) proteins inferred from comparative analyses of amino acid and coding nucleotide sequences. | O Gotoh | J Biol Chem | 1992 | 1730627 | Yes |
| 3770 | 1010 | 1010.0 | 28.1 | 28.1 | The role of protein phosphorylation in neural and hormonal control of cellular activity. | P Cohen | Nature | 1982 | 6280056 | False |
| 3771 | 1010 | 1010.0 | 33.0 | 33.0 | Solid dispersion of poorly water-soluble drugs: early promises, subsequent problems, and recent breakthroughs. | A T Serajuddin | J Pharm Sci | 1999 | 10514356 | False |
| 3772 | 2020 | 1010.0 | 44.6 | 22.3 | Drug penetration in solid tumours. | Andrew I Minchinton, Ian F Tannock | Nat Rev Cancer | 2006 | 16862189 | False |
| 3773 | 3029 | 1009.7 | 76.3 | 25.4 | The distributed human neural system for face perception. | J V Haxby, E A Hoffman, M I Gobbini | Trends Cogn Sci | 2000 | 10827445 | Yes |
| 3774 | 2019 | 1009.5 | 59.6 | 29.8 | The biochemical basis of zinc physiology. | B L Vallee, K H Falchuk | Physiol Rev | 1993 | 8419966 | False |
| 3775 | 1009 | 1009.0 | 69.9 | 69.9 | Maxillary and sinus implant reconstructions. | H Tatum | Dent Clin North Am | 1986 | 3516738 | Yes |
| 3776 | 1009 | 1009.0 | 28.6 | 28.6 | Intermediate filaments: a chemically heterogeneous, developmentally regulated class of proteins. | E Lazarides | Annu Rev Biochem | 1982 | 6180679 | False |
| 3777 | 1009 | 1009.0 | 53.6 | 53.6 | Comparative pharmacology of calcium antagonists: nifedipine, verapamil and diltiazem. | P D Henry | Am J Cardiol | 1980 | 6255787 | False |
| 3778 | 1009 | 1009.0 | 20.6 | 20.6 | Apoptotic pathways: the roads to ruin. | D R Green | Cell | 1998 | 9753316 | False |
| 3779 | 1009 | 1009.0 | 21.8 | 21.8 | Tamoxifen in the treatment of breast cancer. | C K Osborne | N Engl J Med | 1998 | 9828250 | False |
| 3780 | 1009 | 1009.0 | 23.7 | 23.7 | The 5-choice serial reaction time task: behavioural pharmacology and functional neurochemistry. | T W Robbins | Psychopharmacology (Berl) | 2002 | 12373437 | False |
| 3781 | 1009 | 1009.0 | 31.9 | 31.9 | Nicotine addiction. | Neal L Benowitz | N Engl J Med | 2010 | 20554984 | False |
| 3782 | 2016 | 1008.0 | 48.1 | 24.1 | A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. | G L Semenza, G L Wang | Mol Cell Biol | 1992 | 1448077 | Yes |
| 3783 | 1008 | 1008.0 | 16.4 | 16.4 | SCF and Cullin/Ring H2-based ubiquitin ligases. | R J Deshaies | Annu Rev Cell Dev Biol | 1999 | 10611969 | False |
| 3784 | 1008 | 1008.0 | 24.9 | 24.9 | Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment. | B Halliwell | Drugs Aging | 2001 | 11599635 | False |
| 3785 | 1008 | 1008.0 | 30.0 | 30.0 | Using chemical shift perturbation to characterise ligand binding. | Mike P Williamson | Prog Nucl Magn Reson Spectrosc | 2013 | 23962882 | False |
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| 3787 | 3023 | 1007.7 | 90.5 | 30.2 | Contribution of primary care to health systems and health. | Barbara Starfield, Leiyu Shi, James Macinko | Milbank Q | 2005 | 16202000 | False |
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| 3790 | 1007 | 1007.0 | 26.7 | 26.7 | The neurobiology of startle. | M Koch | Prog Neurobiol | 1999 | 10463792 | False |
| 3791 | 1007 | 1007.0 | 26.3 | 26.3 | The underappreciated role of muscle in health and disease. | Robert R Wolfe | Am J Clin Nutr | 2006 | 16960159 | False |
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| 3794 | 1006 | 1006.0 | 27.4 | 27.4 | Utility of food-specific IgE concentrations in predicting symptomatic food allergy. | H A Sampson | J Allergy Clin Immunol | 2001 | 11344358 | Yes |
| 3795 | 2012 | 1006.0 | 53.3 | 26.6 | Chemical Redox Agents for Organometallic Chemistry. | Neil G. Connelly, William E. Geiger | Chem Rev | 1996 | 11848774 | Yes |
| 3796 | 1006 | 1006.0 | 20.5 | 20.5 | DNA and its associated processes as targets for cancer therapy. | Laurence H Hurley | Nat Rev Cancer | 2002 | 11990855 | False |
| 3797 | 1006 | 1006.0 | 27.6 | 27.6 | Clinical practice. The thyroid nodule. | Laszlo Hegedüs | N Engl J Med | 2004 | 15496625 | False |
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| 3800 | 2011 | 1005.5 | 43.4 | 21.7 | Hsp70 chaperones: cellular functions and molecular mechanism. | M P Mayer, B Bukau | Cell Mol Life Sci | 2005 | 15770419 | False |
| 3801 | 1005 | 1005.0 | 45.3 | 45.3 | The serotonin syndrome. | H Sternbach | Am J Psychiatry | 1991 | 2035713 | False |
| 3802 | 1005 | 1005.0 | 19.9 | 19.9 | Tumor heterogeneity. | G H Heppner | Cancer Res | 1984 | 6372991 | False |
| 3803 | 1005 | 1005.0 | 18.0 | 18.0 | The 5' ends of Drosophila heat shock genes in chromatin are hypersensitive to DNase I. | C Wu | Nature | 1980 | 6774262 | Yes |
| 3804 | 1005 | 1005.0 | 28.6 | 28.6 | Measuring reward with the conditioned place preference paradigm: a comprehensive review of drug effects, recent progress and new issues. | T M Tzschentke | Prog Neurobiol | 1998 | 9871940 | False |
| 3805 | 1005 | 1005.0 | 23.4 | 23.4 | Nrf2 signaling in coordinated activation of antioxidant gene expression. | Anil K Jaiswal | Free Radic Biol Med | 2004 | 15110384 | False |
| 3806 | 1005 | 1005.0 | 23.6 | 23.6 | MAPK signalling pathways as molecular targets for anti-inflammatory therapy--from molecular mechanisms to therapeutic benefits. | Bozena Kaminska | Biochim Biophys Acta | 2005 | 16198162 | False |
| 3807 | 2009 | 1004.5 | 40.9 | 20.4 | High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal. | Michael T Lotze, Kevin J Tracey | Nat Rev Immunol | 2005 | 15803152 | False |
| 3808 | 1004 | 1004.0 | 26.9 | 26.9 | The molecular biology and functions of the granulocyte-macrophage colony-stimulating factors. | D Metcalf | Blood | 1986 | 3002522 | False |
| 3809 | 1004 | 1004.0 | 20.2 | 20.2 | Selective mitochondrial autophagy, or mitophagy, as a targeted defense against oxidative stress, mitochondrial dysfunction, and aging. | John J Lemasters | Rejuvenation Res | 2005 | 15798367 | Yes |
| 3810 | 1004 | 1004.0 | 27.1 | 27.1 | Integrating mechanisms of pulmonary fibrosis. | Thomas A Wynn | J Exp Med | 2011 | 21727191 | False |
| 3811 | 1004 | 1004.0 | 30.4 | 30.4 | Gut feelings: the emerging biology of gut-brain communication. | Emeran A Mayer | Nat Rev Neurosci | 2011 | 21750565 | False |
| 3812 | 3012 | 1004.0 | 81.6 | 27.2 | Innate and adaptive immune cells in the tumor microenvironment. | Thomas F Gajewski, Hans Schreiber, Yang-Xin Fu | Nat Immunol | 2013 | 24048123 | False |
| 3813 | 2007 | 1003.5 | 67.7 | 33.9 | Simulation study of confounder-selection strategies. | G Maldonado, S Greenland | Am J Epidemiol | 1993 | 8256780 | Yes |
| 3814 | 2007 | 1003.5 | 70.0 | 35.0 | Loneliness matters: a theoretical and empirical review of consequences and mechanisms. | Louise C Hawkley, John T Cacioppo | Ann Behav Med | 2010 | 20652462 | False |
| 3815 | 2007 | 1003.5 | 93.0 | 46.5 | Biological Functions of Autophagy Genes: A Disease Perspective. | Beth Levine, Guido Kroemer | Cell | 2019 | 30633901 | False |
| 3816 | 1003 | 1003.0 | 56.6 | 56.6 | Problems, obstacles, and complications of limb lengthening by the Ilizarov technique. | D Paley | Clin Orthop Relat Res | 1990 | 2403498 | False |
| 3817 | 1003 | 1003.0 | 28.3 | 28.3 | Structure and function of voltage-sensitive ion channels. | W A Catterall | Science | 1988 | 2459775 | False |
| 3818 | 1003 | 1003.0 | 30.1 | 30.1 | Inactivation of antibiotics and the dissemination of resistance genes. | J Davies | Science | 1994 | 8153624 | False |
| 3819 | 1003 | 1003.0 | 34.6 | 34.6 | Review of second-order models for adsorption systems. | Yuh-Shan Ho | J Hazard Mater | 2006 | 16460877 | False |
| 3820 | 1003 | 1003.0 | 32.5 | 32.5 | Measures of Diagnostic Accuracy: Basic Definitions. | Ana-Maria Šimundić | EJIFCC | 2009 | 27683318 | Yes |
| 3821 | 2005 | 1002.5 | 53.0 | 26.5 | The mitochondrial permeability transition. | M Zoratti, I Szabò | Biochim Biophys Acta | 1995 | 7640294 | False |
| 3822 | 2005 | 1002.5 | 44.4 | 22.2 | A molecular mechanism for the effect of lithium on development. | P S Klein, D A Melton | Proc Natl Acad Sci U S A | 1996 | 8710892 | Yes |
| 3823 | 2005 | 1002.5 | 57.3 | 28.6 | Regulatory networks defining EMT during cancer initiation and progression. | Bram De Craene, Geert Berx | Nat Rev Cancer | 2013 | 23344542 | False |
| 3824 | 2004 | 1002.0 | 46.8 | 23.4 | p53 function and dysfunction. | B Vogelstein, K W Kinzler | Cell | 1992 | 1505019 | False |
| 3825 | 1002 | 1002.0 | 20.2 | 20.2 | Prion diseases of humans and animals: their causes and molecular basis. | J Collinge | Annu Rev Neurosci | 2001 | 11283320 | False |
| 3826 | 2004 | 1002.0 | 50.1 | 25.1 | The anti-inflammatory effect of exercise. | Anne Marie W Petersen, Bente Klarlund Pedersen | J Appl Physiol (1985) | 2005 | 15772055 | False |
| 3827 | 2004 | 1002.0 | 65.0 | 32.5 | Required sample size to detect the mediated effect. | Matthew S Fritz, David P Mackinnon | Psychol Sci | 2007 | 17444920 | Yes |
| 3828 | 1002 | 1002.0 | 30.3 | 30.3 | The epidemiology of urinary tract infection. | Betsy Foxman | Nat Rev Urol | 2010 | 21139641 | False |
| 3829 | 2004 | 1002.0 | 52.3 | 26.1 | Macrophages in the pathogenesis of atherosclerosis. | Kathryn J Moore, Ira Tabas | Cell | 2011 | 21529710 | False |
| 3830 | 1001 | 1001.0 | 37.2 | 37.2 | Hazards of hospitalization of the elderly. | M C Creditor | Ann Intern Med | 1993 | 8417639 | False |
| 3831 | 3003 | 1001.0 | 70.8 | 23.6 | Prognosis of hepatocellular carcinoma: the BCLC staging classification. | J M Llovet, C Brú, J Bruix | Semin Liver Dis | 1999 | 10518312 | Yes |
| 3832 | 1001 | 1001.0 | 22.3 | 22.3 | Natural history of chronic hepatitis C. | Leonard B Seeff | Hepatology | 2002 | 12407575 | False |
| 3833 | 1001 | 1001.0 | 28.2 | 28.2 | Insecticide-treated bed nets and curtains for preventing malaria. | C Lengeler | Cochrane Database Syst Rev | 2004 | 15106149 | Yes |
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| 3835 | 1001 | 1001.0 | 41.3 | 41.3 | The theory of planned behaviour: reactions and reflections. | Icek Ajzen | Psychol Health | 2011 | 21929476 | False |
| 3836 | 3002 | 1000.7 | 82.7 | 27.6 | Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. | J Lazarou, B H Pomeranz, P N Corey | JAMA | 1998 | 9555760 | Yes |
| 3837 | 1000 | 1000.0 | 33.7 | 33.7 | A practical computer-based approach to the analysis of radioligand binding experiments. | G A McPherson | Comput Programs Biomed | 1983 | 6319079 | Yes |
| 3838 | 1000 | 1000.0 | 24.1 | 24.1 | Disorders of the cerebellum: ataxia, dysmetria of thought, and the cerebellar cognitive affective syndrome. | Jeremy D Schmahmann | J Neuropsychiatry Clin Neurosci | 2004 | 15377747 | False |
| 3839 | 1000 | 1000.0 | 31.8 | 31.8 | Mode of questionnaire administration can have serious effects on data quality. | Ann Bowling | J Public Health (Oxf) | 2005 | 15870099 | False |
| 3840 | 1999 | 999.5 | 39.3 | 19.6 | The two NF-kappaB activation pathways and their role in innate and adaptive immunity. | Giuseppina Bonizzi, Michael Karin | Trends Immunol | 2004 | 15145317 | False |
| 3841 | 1999 | 999.5 | 83.4 | 41.7 | Removal of heavy metal ions from wastewaters: a review. | Fenglian Fu, Qi Wang | J Environ Manage | 2011 | 21138785 | False |
| 3842 | 999 | 999.0 | 20.4 | 20.4 | Protein glycosylation: nature, distribution, enzymatic formation, and disease implications of glycopeptide bonds. | Robert G Spiro | Glycobiology | 2002 | 12042244 | False |
| 3843 | 998 | 998.0 | 17.7 | 17.7 | Translational regulation of GCN4 and the general amino acid control of yeast. | Alan G Hinnebusch | Annu Rev Microbiol | 2005 | 16153175 | False |
| 3844 | 998 | 998.0 | 25.8 | 25.8 | Effects of protein aggregates: an immunologic perspective. | Amy S Rosenberg | AAPS J | 2006 | 17025268 | False |
| 3845 | 6985 | 997.9 | 484.7 | 69.2 | IQ-TREE 2: New Models and Efficient Methods for Phylogenetic Inference in the Genomic Era. | Bui Quang Minh, Heiko A Schmidt, Olga Chernomor, Dominik Schrempf, Michael D Woodhams, Arndt von Haeseler, Robert Lanfear | Mol Biol Evol | 2020 | 32011700 | Yes |
| 3846 | 1995 | 997.5 | 62.9 | 31.4 | Structure and function of the brain serotonin system. | B L Jacobs, E C Azmitia | Physiol Rev | 1992 | 1731370 | False |
| 3847 | 1995 | 997.5 | 154.8 | 77.4 | TYGS is an automated high-throughput platform for state-of-the-art genome-based taxonomy. | Jan P Meier-Kolthoff, Markus Göker | Nat Commun | 2019 | 31097708 | Yes |
| 3848 | 2991 | 997.0 | 87.2 | 29.1 | Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill. | M B Hansen, S E Nielsen, K Berg | J Immunol Methods | 1989 | 2470825 | Yes |
| 3849 | 996 | 996.0 | 24.7 | 24.7 | Erythropoietin. | S B Krantz | Blood | 1991 | 1991159 | False |
| 3850 | 996 | 996.0 | 31.2 | 31.2 | The hibernating myocardium. | S H Rahimtoola | Am Heart J | 1989 | 2783527 | Yes |
| 3851 | 2988 | 996.0 | 113.6 | 37.9 | The twenty-item Toronto Alexithymia Scale--I. Item selection and cross-validation of the factor structure. | R M Bagby, J D Parker, G J Taylor | J Psychosom Res | 1994 | 8126686 | Yes |
| 3852 | 996 | 996.0 | 27.8 | 27.8 | Assessment and development of executive function (EF) during childhood. | Peter Anderson | Child Neuropsychol | 2002 | 12638061 | Yes |
| 3853 | 996 | 996.0 | 28.4 | 28.4 | The broaden-and-build theory of positive emotions. | Barbara L Fredrickson | Philos Trans R Soc Lond B Biol Sci | 2004 | 15347528 | False |
| 3854 | 1992 | 996.0 | 63.8 | 31.9 | An overview of mortality and sequelae of preterm birth from infancy to adulthood. | Saroj Saigal, Lex W Doyle | Lancet | 2008 | 18207020 | False |
| 3855 | 996 | 996.0 | 22.1 | 22.1 | Genomewide association studies and assessment of the risk of disease. | Teri A Manolio | N Engl J Med | 2010 | 20647212 | False |
| 3856 | 1992 | 996.0 | 86.5 | 43.2 | Network analysis: an integrative approach to the structure of psychopathology. | Denny Borsboom, Angélique O J Cramer | Annu Rev Clin Psychol | 2013 | 23537483 | False |
| 3857 | 1991 | 995.5 | 108.9 | 54.5 | Making Neighborhood-Disadvantage Metrics Accessible - The Neighborhood Atlas. | Amy J H Kind, William R Buckingham | N Engl J Med | 2018 | 29949490 | Yes |
| 3858 | 4976 | 995.2 | 134.7 | 26.9 | From inflammation to sickness and depression: when the immune system subjugates the brain. | Robert Dantzer, Jason C O'Connor, Gregory G Freund, Rodney W Johnson, Keith W Kelley | Nat Rev Neurosci | 2008 | 18073775 | False |
| 3859 | 1990 | 995.0 | 75.6 | 37.8 | The development of a six-item short-form of the state scale of the Spielberger State-Trait Anxiety Inventory (STAI). | T M Marteau, H Bekker | Br J Clin Psychol | 1992 | 1393159 | Yes |
| 3860 | 995 | 995.0 | 29.3 | 29.3 | Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man. | W E Roediger | Gut | 1980 | 7429343 | Yes |
| 3861 | 995 | 995.0 | 19.1 | 19.1 | Mechanisms and functions of DNA mismatch repair. | Guo-Min Li | Cell Res | 2008 | 18157157 | False |
| 3862 | 995 | 995.0 | 30.1 | 30.1 | Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway. | Vassiliki A Boussiotis | N Engl J Med | 2016 | 27806234 | False |
| 3863 | 1989 | 994.5 | 74.6 | 37.3 | MMseqs2 enables sensitive protein sequence searching for the analysis of massive data sets. | Martin Steinegger, Johannes Söding | Nat Biotechnol | 2017 | 29035372 | Yes |
| 3864 | 2983 | 994.3 | 95.8 | 31.9 | A simplified ultrasensitive silver stain for detecting proteins in polyacrylamide gels. | B R Oakley, D R Kirsch, N R Morris | Anal Biochem | 1980 | 6161559 | Yes |
| 3865 | 994 | 994.0 | 40.6 | 40.6 | Stress, coping, and social support processes: where are we? What next? | P A Thoits | J Health Soc Behav | 1995 | 7560850 | False |
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| 3867 | 994 | 994.0 | 27.6 | 27.6 | Prediction of human clearance of twenty-nine drugs from hepatic microsomal intrinsic clearance data: An examination of in vitro half-life approach and nonspecific binding to microsomes. | R S Obach | Drug Metab Dispos | 1999 | 10534321 | Yes |
| 3868 | 994 | 994.0 | 20.6 | 20.6 | The state of lipid rafts: from model membranes to cells. | Michael Edidin | Annu Rev Biophys Biomol Struct | 2003 | 12543707 | False |
| 3869 | 994 | 994.0 | 23.6 | 23.6 | The miR-34 family in cancer and apoptosis. | H Hermeking | Cell Death Differ | 2010 | 19461653 | False |
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| 3871 | 1987 | 993.5 | 49.6 | 24.8 | Reactivation of hippocampal ensemble memories during sleep. | M A Wilson, B L McNaughton | Science | 1994 | 8036517 | Yes |
| 3872 | 3974 | 993.5 | 133.8 | 33.5 | Comparison of Beck Depression Inventories -IA and -II in psychiatric outpatients. | A T Beck, R A Steer, R Ball, W Ranieri | J Pers Assess | 1996 | 8991972 | Yes |
| 3873 | 1987 | 993.5 | 47.7 | 23.9 | Ab initio molecular dynamics for open-shell transition metals. | G Kresse, J Hafner | Phys Rev B Condens Matter | 1993 | 10007687 | Yes |
| 3874 | 1987 | 993.5 | 44.8 | 22.4 | Piezoelectric nanogenerators based on zinc oxide nanowire arrays. | Zhong Lin Wang, Jinhui Song | Science | 2006 | 16614215 | Yes |
| 3875 | 993 | 993.0 | 27.1 | 27.1 | Biochemistry of endotoxins. | C R Raetz | Annu Rev Biochem | 1990 | 1695830 | False |
| 3876 | 993 | 993.0 | 29.0 | 29.0 | Tissue factor and hemostasis. | Y Nemerson | Blood | 1988 | 3275472 | False |
| 3877 | 993 | 993.0 | 28.2 | 28.2 | Peptide antibiotics. | R E Hancock | Lancet | 1997 | 9033483 | False |
| 3878 | 993 | 993.0 | 24.2 | 24.2 | Medical consequences of obesity. | George A Bray | J Clin Endocrinol Metab | 2004 | 15181027 | False |
| 3879 | 2978 | 1489.0 | 77.7 | 38.9 | Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. | B R Celli, W MacNee | Eur Respir J | 2004 | 15219010 | False |
| 3880 | 1985 | 992.5 | 41.9 | 20.9 | Molecular mechanisms of mTOR-mediated translational control. | Xiaoju Max Ma, John Blenis | Nat Rev Mol Cell Biol | 2009 | 19339977 | False |
| 3881 | 1985 | 992.5 | 40.6 | 20.3 | The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. | Skirmantas Kriaucionis, Nathaniel Heintz | Science | 2009 | 19372393 | Yes |
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| 3884 | 1984 | 992.0 | 44.2 | 22.1 | Helicobacter pylori infection. | Sebastian Suerbaum, Pierre Michetti | N Engl J Med | 2002 | 12374879 | False |
| 3885 | 992 | 992.0 | 27.3 | 27.3 | The meaning of translational research and why it matters. | Steven H Woolf | JAMA | 2008 | 18182604 | Yes |
| 3886 | 992 | 992.0 | 19.6 | 19.6 | Epistasis--the essential role of gene interactions in the structure and evolution of genetic systems. | Patrick C Phillips | Nat Rev Genet | 2008 | 18852697 | False |
| 3887 | 2976 | 992.0 | 96.9 | 32.3 | xCell: digitally portraying the tissue cellular heterogeneity landscape. | Dvir Aran, Zicheng Hu, Atul J Butte | Genome Biol | 2017 | 29141660 | Yes |
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| 3889 | 1982 | 991.0 | 36.2 | 18.1 | Signal transduction by lymphocyte antigen receptors. | A Weiss, D R Littman | Cell | 1994 | 8293463 | False |
| 3890 | 991 | 991.0 | 27.1 | 27.1 | The outcome of anorexia nervosa in the 20th century. | Hans-Christoph Steinhausen | Am J Psychiatry | 2002 | 12153817 | False |
| 3891 | 1982 | 991.0 | 42.5 | 21.2 | The many roles of chemokines and chemokine receptors in inflammation. | Israel F Charo, Richard M Ransohoff | N Engl J Med | 2006 | 16467548 | False |
| 3892 | 991 | 991.0 | 36.7 | 36.7 | The CRISPR tool kit for genome editing and beyond. | Mazhar Adli | Nat Commun | 2018 | 29765029 | False |
| 3893 | 3963 | 990.8 | 174.1 | 43.5 | Measurement of patient outcome in arthritis. | J F Fries, P Spitz, R G Kraines, H R Holman | Arthritis Rheum | 1980 | 7362664 | Yes |
| 3894 | 1981 | 990.5 | 50.2 | 25.1 | Drug addiction, dysregulation of reward, and allostasis. | G F Koob, M Le Moal | Neuropsychopharmacology | 2001 | 11120394 | False |
| 3895 | 1981 | 990.5 | 48.3 | 24.1 | Latest advances in understanding preeclampsia. | Christopher W Redman, Ian L Sargent | Science | 2005 | 15947178 | False |
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| 3898 | 990 | 990.0 | 26.3 | 26.3 | Erectile dysfunction. | T F Lue | N Engl J Med | 2000 | 10853004 | False |
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| 3902 | 1978 | 989.0 | 38.8 | 19.4 | I kappa B: a specific inhibitor of the NF-kappa B transcription factor. | P A Baeuerle, D Baltimore | Science | 1988 | 3140380 | Yes |
| 3903 | 989 | 989.0 | 33.4 | 33.4 | Minamata disease: methylmercury poisoning in Japan caused by environmental pollution. | M Harada | Crit Rev Toxicol | 1995 | 7734058 | False |
| 3904 | 1978 | 989.0 | 41.4 | 20.7 | The mechanisms of action of PPARs. | Joel Berger, David E Moller | Annu Rev Med | 2002 | 11818483 | False |
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| 3906 | 989 | 989.0 | 25.0 | 25.0 | The influence of social hierarchy on primate health. | Robert M Sapolsky | Science | 2005 | 15860617 | False |
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| 3915 | 1975 | 987.5 | 39.7 | 19.9 | p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21. | H Toyoshima, T Hunter | Cell | 1994 | 8033213 | Yes |
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| 3917 | 1974 | 987.0 | 57.3 | 28.6 | The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. | D W Choi, S M Rothman | Annu Rev Neurosci | 1990 | 1970230 | False |
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| 3990 | 1957 | 978.5 | 39.5 | 19.8 | p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest. | G J Hannon, D Beach | Nature | 1994 | 8078588 | Yes |
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| 4020 | 1948 | 974.0 | 57.5 | 28.8 | Luminescent carbon nanodots: emergent nanolights. | Sheila N Baker, Gary A Baker | Angew Chem Int Ed Engl | 2010 | 20687055 | Yes |
| 4021 | 2921 | 973.7 | 110.3 | 36.8 | Distinguishing optimism from neuroticism (and trait anxiety, self-mastery, and self-esteem): a reevaluation of the Life Orientation Test. | M F Scheier, C S Carver, M W Bridges | J Pers Soc Psychol | 1994 | 7815302 | Yes |
| 4022 | 1947 | 973.5 | 57.4 | 28.7 | A simple method of reducing the fading of immunofluorescence during microscopy. | G D Johnson, G M Nogueira Araujo | J Immunol Methods | 1981 | 7019347 | Yes |
| 4023 | 1947 | 973.5 | 89.4 | 44.7 | EMT Transition States during Tumor Progression and Metastasis. | Ievgenia Pastushenko, Cédric Blanpain | Trends Cell Biol | 2019 | 30594349 | False |
| 4024 | 973 | 973.0 | 19.8 | 19.8 | A thousand and one protein kinases. | T Hunter | Cell | 1987 | 3113737 | False |
| 4025 | 1946 | 973.0 | 46.0 | 23.0 | Creatine and creatinine metabolism. | M Wyss, R Kaddurah-Daouk | Physiol Rev | 2000 | 10893433 | False |
| 4026 | 1946 | 973.0 | 45.2 | 22.6 | Gut flora in health and disease. | Francisco Guarner, Juan-R Malagelada | Lancet | 2003 | 12583961 | False |
| 4027 | 973 | 973.0 | 25.6 | 25.6 | Potential synergy of phytochemicals in cancer prevention: mechanism of action. | Rui Hai Liu | J Nutr | 2004 | 15570057 | False |
| 4028 | 5836 | 972.7 | 162.4 | 27.1 | Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. | Q L Choo, G Kuo, A J Weiner, L R Overby, D W Bradley, M Houghton | Science | 1989 | 2523562 | Yes |
| 4029 | 1945 | 972.5 | 64.9 | 32.5 | Pain: a review of three commonly used pain rating scales. | Amelia Williamson, Barbara Hoggart | J Clin Nurs | 2005 | 16000093 | False |
| 4030 | 5833 | 972.2 | 204.5 | 34.1 | The Neuropsychiatric Inventory: comprehensive assessment of psychopathology in dementia. | J L Cummings, M Mega, K Gray, S Rosenberg-Thompson, D A Carusi, J Gornbein | Neurology | 1994 | 7991117 | Yes |
| 4031 | 972 | 972.0 | 23.1 | 23.1 | Oncogenes, antioncogenes, and the molecular bases of multistep carcinogenesis. | R A Weinberg | Cancer Res | 1989 | 2660980 | False |
| 4032 | 972 | 972.0 | 30.2 | 30.2 | Natural history of cervical intraepithelial neoplasia: a critical review. | A G Ostör | Int J Gynecol Pathol | 1993 | 8463044 | False |
| 4033 | 972 | 972.0 | 21.8 | 21.8 | Entropy production fluctuation theorem and the nonequilibrium work relation for free energy differences. | G E Crooks | Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics | 1999 | 11970075 | Yes |
| 4034 | 1944 | 972.0 | 40.0 | 20.0 | Molecular dynamics simulations of biomolecules. | Martin Karplus, J Andrew McCammon | Nat Struct Biol | 2002 | 12198485 | False |
| 4035 | 972 | 972.0 | 22.9 | 22.9 | Calcium cycling and signaling in cardiac myocytes. | Donald M Bers | Annu Rev Physiol | 2008 | 17988210 | False |
| 4036 | 972 | 972.0 | 30.2 | 30.2 | Defining 'Evolutionarily Significant Units' for conservation. | C Moritz | Trends Ecol Evol | 1994 | 21236896 | Yes |
| 4037 | 1944 | 972.0 | 88.6 | 44.3 | Introduction to the human gut microbiota. | Elizabeth Thursby, Nathalie Juge | Biochem J | 2017 | 28512250 | False |
| 4038 | 1943 | 971.5 | 46.6 | 23.3 | Production of large amounts of hydrogen peroxide by human tumor cells. | T P Szatrowski, C F Nathan | Cancer Res | 1991 | 1846317 | Yes |
| 4039 | 1943 | 971.5 | 93.4 | 46.7 | Illusion and well-being: a social psychological perspective on mental health. | S E Taylor, J D Brown | Psychol Bull | 1988 | 3283814 | False |
| 4040 | 1943 | 971.5 | 74.3 | 37.1 | Mechanisms of hepatic stellate cell activation. | Takuma Tsuchida, Scott L Friedman | Nat Rev Gastroenterol Hepatol | 2017 | 28487545 | False |
| 4041 | 2914 | 971.3 | 72.4 | 24.1 | Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells. | B Devika Chithrani, Arezou A Ghazani, Warren C W Chan | Nano Lett | 2006 | 16608261 | Yes |
| 4042 | 971 | 971.0 | 38.9 | 38.9 | NMR spectroscopy in the structural elucidation of oligosaccharides and glycosides. | P K Agrawal | Phytochemistry | 1992 | 1368855 | False |
| 4043 | 971 | 971.0 | 17.3 | 17.3 | Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis. | M J Lenardo | Nature | 1991 | 1944559 | Yes |
| 4044 | 1942 | 971.0 | 47.7 | 23.9 | Multiple myeloma. | Antonio Palumbo, Kenneth Anderson | N Engl J Med | 2011 | 21410373 | False |
| 4045 | 2913 | 971.0 | 95.6 | 31.9 | Remodelling the extracellular matrix in development and disease. | Caroline Bonnans, Jonathan Chou, Zena Werb | Nat Rev Mol Cell Biol | 2014 | 25415508 | False |
| 4046 | 971 | 971.0 | 30.4 | 30.4 | Best Practices for QSAR Model Development, Validation, and Exploitation. | Alexander Tropsha | Mol Inform | 2010 | 27463326 | False |
| 4047 | 2912 | 970.7 | 58.8 | 19.6 | Tumour stem cells and drug resistance. | Michael Dean, Tito Fojo, Susan Bates | Nat Rev Cancer | 2005 | 15803154 | False |
| 4048 | 970 | 970.0 | 22.8 | 22.8 | iNOS-mediated nitric oxide production and its regulation. | Fugen Aktan | Life Sci | 2004 | 15172174 | False |
| 4049 | 9700 | 1077.8 | 381.0 | 42.3 | QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. | Penny F Whiting, Anne W S Rutjes, Marie E Westwood, Susan Mallett, Jonathan J Deeks, Johannes B Reitsma, Mariska M G Leeflang, Jonathan A C Sterne, Patrick M M Bossuyt | Ann Intern Med | 2011 | 22007046 | Yes |
| 4050 | 4849 | 969.8 | 139.8 | 28.0 | Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. | D Levy, R J Garrison, D D Savage, W B Kannel, W P Castelli | N Engl J Med | 1990 | 2139921 | Yes |
| 4051 | 1939 | 969.5 | 43.1 | 21.6 | Independent component analysis: algorithms and applications. | A Hyvärinen, E Oja | Neural Netw | 2000 | 10946390 | Yes |
| 4052 | 1939 | 969.5 | 45.4 | 22.7 | Epigenetic modifications and human disease. | Anna Portela, Manel Esteller | Nat Biotechnol | 2010 | 20944598 | False |
| 4053 | 3878 | 969.5 | 140.2 | 35.0 | Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010. | Katherine M Flegal, Margaret D Carroll, Brian K Kit, Cynthia L Ogden | JAMA | 2012 | 22253363 | Yes |
| 4054 | 2908 | 969.3 | 89.5 | 29.8 | Calibration of the Computer Science and Applications, Inc. accelerometer. | P S Freedson, E Melanson, J Sirard | Med Sci Sports Exerc | 1998 | 9588623 | Yes |
| 4055 | 4846 | 969.2 | 111.2 | 22.2 | Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. | J G Herman, J R Graff, S Myöhänen, B D Nelkin, S B Baylin | Proc Natl Acad Sci U S A | 1996 | 8790415 | Yes |
| 4056 | 969 | 969.0 | 25.1 | 25.1 | Advanced glycation endproducts--role in pathology of diabetic complications. | Nessar Ahmed | Diabetes Res Clin Pract | 2005 | 15620429 | False |
| 4057 | 2906 | 968.7 | 75.1 | 25.0 | Epidemiology of obstructive sleep apnea: a population health perspective. | Terry Young, Paul E Peppard, Daniel J Gottlieb | Am J Respir Crit Care Med | 2002 | 11991871 | False |
| 4058 | 1937 | 968.5 | 54.4 | 27.2 | Socioeconomic status and child development. | Robert H Bradley, Robert F Corwyn | Annu Rev Psychol | 2002 | 11752490 | False |
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